- April 22, 2020.
Our college’s web site advertises that the laboratory and its collaborators at the universities of Georgia and Mississippi have been awarded two NIH grants to investigate the role of airway epithelial reactive oxygen species in defense against influenza viruses and pneumococcus.
- January 2019.
Our report titled “Systemic levels of anti-PAD4 autoantibodies correlate with airway obstruction in cystic fibrosis” published in The Journal of Cystic Fibrosis has been featured online. This collaborative work identified a new autoantibody in cystic fibrosis patients. These autoantibodies target a protein, PAD4, that is highly expressed in neutrophils and mediates a key antimicrobial function of the cells, the release of neutrophil extracellular traps.
- April 2018.
The National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH) awarded an R01 grant to our laboratory and collaborators at the Emory Cystic Fibrosis Center to study neutrophil-mediated inflammation in cystic fibrosis. This good news have been advertised online.
- November 2016.
Our article titled “Swimming motility mediates the formation of neutrophil extracellular traps induced by flagellated Pseudomonas aeruginosa” published in PLoS Pathogens has been cited by several scientific online news sites. This study identified the ability of the flagellum to drive bacterial motility as a central factor of Pseudomonas aeruginosa to interact with key immune cells called neutrophil granulocytes. A detailed characterization of the crucial role flagellar motility plays in bacterial activation of immune cells by our study has relevance to better understand acute and chronic P. aeruginosa infections in humans such as in cystic fibrosis patients.